Provider Alert! Adakveo Update

Provider Alert!

Provider Alert! Adakveo Update

Attention: Hematologists
Effective Date: May 26, 2020

Call to action: Adakveo, Injection, crizanlizumab – clinician administered drug HCPCS code C9053 is an at risk drug. Currently, there is no prior authorization required; however, beginning May 26, 2020 authorization guidelines will be in place. The required criteria to receive Adakveo include:

  • HbSS (sickle cell) diagnosis
  • Patients over the age of 16 years-old
  • Patients that have experienced more than two vaso-occlusive crisis (VOC) events in the past 12-months

How this impacts providers: Prescribers should adhere to the guidelines and acquire the necessary prior-authorizations.


TMPPM criteria is pending publication therefore, peer reviewed literature will be applied in absence of state criteria.

Next steps for providers: Prescribers should regularly check the prior authorization requirements with the Texas vendor Drug Program:

If you have any questions, please email Provider Network Management at:

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